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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

A |     杭州日报讯 填不完的表格、开不完的会议、迎不完的检查，让许多村干部疲于应付，走村入户、服务群众的时间反而被一再挤压。

B |     Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。

C | 让村干部从“文山会海”中解放出来，是基层治理必须答好的考卷。

D | 以清单明确边界，把好事项准入关。负担沉重，根源在于权责不清。

E | 要全面梳理依法履职和协助办理事项，列明“该干什么、不该干什么”，形成权责清晰的履职清单。清单之外事项一律实行准入审批，坚持“权随责走、费随事转”。厘清权责，是让村干部干该干的事。以精简卸下包袱，告别“指尖形式主义”。要敢于对冗余App和工作群“动刀子”，能合则合、该取消则取消。从“重留痕”转向“重实效”，纠正“打卡式”考核。推行数据共享，实现“一次采集、多方共享”。

F | 萧山区近年来持续推进减负工作，着力把村干部从“指尖”上解脱出来，让他们把双脚踏进泥土里。以下沉回归本业，用实干回应民需。减负的目的是让村干部有更多精力办实事。要建立以解决实际问题、群众满意为导向的考核机制，不以材料论英雄，而以口碑作标尺。推动常态化入户走访，变“群众找上门”为“干部送上门”，腾出的时间用来倾听难处、关爱老人、谋划发展。当村干部从“填表员”“会议员”回归“服务员”，基层治理才能真正做到“民有所呼、我有所应”。厘清权责、治理指尖形式主义、推动干部下沉服务，三者同向发力，才能让村干部真正轻装上阵，把减负释放的时间转化为服务实效，让村干部从“案头”走向“地头”，基层治理才能焕发生机与活力。

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Published on:01:30:29